The role of clinical laboratories in lead exposure: from diagnosis of acute poisonings to neonatal screening? A report on two cases
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Keywords

neonatal screening
petrol
poisoning
paint
lead

How to Cite

García-González, E., Calvo-Ruata, L., Founaud, B., Romero-Sánchez, N., & Rello, L. (2016). The role of clinical laboratories in lead exposure: from diagnosis of acute poisonings to neonatal screening? A report on two cases. Spanish Journal of Environmental Health, 16(2), 103–110. Retrieved from https://ojs.diffundit.com/index.php/rsa/article/view/808

Abstract

The role of clinical laboratories in lead exposure has traditionally focused on the diagnosis of poisonings that pose a risk to human health. However, the last decades of the twentieth century saw an increase in public awareness of lead exposure, which prompted the banning of both lead-containing paint and petrol. As a result, acute lead poisonings are increasingly rare in industrialized countries. However, this is always a latent danger that clinicians should be aware of. As an example of this we describe two cases that we recently diagnosed at our laboratory.

Even more worrying is confirming the harmful effects of lead on children, even at concentrations hitherto considered safe. This has renewed interest in the determination of this element in clinical laboratories in order to find and control all those pregnant women and children who might have blood lead levels above a suitable threshold value, which is currently set at 50 μg L-1 for both populations. If this situation becomes the norm, the role of clinical laboratories with respect to lead determination will undergo a major change. This possibility is discussed in this paper, together with a pilot program developed at our hospital for such purpose.

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