Spanish Journal of Environmental Mutagenesis and Genomics

Keynote Lectures

F. Adega

8

Genomic instability: the players and the rules of a risky game

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C. Ladeira

9

Integration of effect biomarkers in human biomonitoring

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H. Louro

10

Impact of genotoxicity data for tackling chemical safety challenges in regulation and health protection

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A. T. Reis, F. Rosário, S. Fraga, C. Costa, J. P. Teixeira

11

What role do nanomaterials play in the evolving world of contaminants of emerging concern?

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C. Jerónimo

12

DNA Methylation: The Rising Potential of Blood-Based Multi-Cancer Early Detection Tests

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Genomic instability, mutagenesis and disease

A. Cué, D. López, J. San Juan, M. Martín, L. Rodríguez, I. Feito, M. I. Sierra, J. Majada, H. Hernández, L. M. Sierra

14

Genotoxic activities of aqueous extracts from Pteridium aquilinum croziers and young fronds and their relationships with their glycoside illudane metabolites

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A. Rodríguez Pescador, L. Gutiérrez Romero, E. Blanco-González, M. Montes-Bayón, L. M. Sierra

15

In vivo evaluation of ultra-small non-magnetic iron oxide nanoparticles using Drosophila melanogaster: potential applications

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N. Miranda, A. Martins-Bessa, I. Gaivão

16

Impact of high sugar diet on male fertility – study in Drosophila melanogaster as a model

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S. Correia, F. Leal, M. Matos

17

Impact of in vitro propagation on genetic stability of two Vaccinium corymbosum varieties

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Biomarkers and biological monitoring

C. Lema-Arranz, A. Hemadeh, N. Cibeira, R. López-López, N. Fernández-Bertólez, J. Méndez, M. Sánchez-Flores, A. Maseda, J. C. Millán-Calenti, J. L. Rodríguez-Villamil, E. Pásaro, V. Valdiglesias, L. Lorenzo-López, B. Laffon

19

Association of genetic and oxidative stress biomarkers with physical and cognitive frailty in older adults

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F. Li, R. Arantes, Z. Gomes, O. Moutinho, I. Gaivão, R. Pinto-Leite

20

Understanding sperm DNA damage: comparative analysis between donors and males in fertility consultations

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V. Sousa, B. Rodrigues, E. Vale-Fernandes, D. Sousa, R. Brandão, C. Leal, I. Gaivão, F. Esteves, S. Costa, J. Pires, J. P. Teixeira, A. J. A. Nogueira, P. Jorge

21

Comet assay reveals a high level of cumulus cells DNA damage in females sharing a phenotype of ovulatory dysfunction

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DNA damage, repair and protection

M. Jordano-Raya, R. R. Ariza, T. Roldán-Arjona, D. Córdoba-Cañero

23

Influence of the orphan base on AP endonuclease activity in Base Excision Repair

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A. Muñoz-Fernández, C. Ayala-Roldán, S. Conde-Maestre, T. Morales-Ruiz, A. L. Gómez, R. R. Ariza, T. Roldán-Arjona, M. I. Martínez-Macías

24

Role of Base Excision Repair in temozolomide-induced DNA damage

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I. Grávalos-Cano, T. Morales-Ruiz, R. R. Ariza, T. Roldán-Arjona, M. I. Martínez-Macías

25

Identification of DNA repair factors involved in resistance of glioblastoma cells to temozolomide

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E. Sáenz-Martínez, A. López de Cerain, A. Azqueta

26

Can bulky adducts be detected by employing the comet assay along with DNA repair inhibitors?

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S. Gonçalves, F. Peixoto, I. Gaivão

27

Unlocking Nature's Shield: Elderberry Hydrosol's Antigenotoxicological and Antioxidant Potential for Sustainable Skincare

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A. Neto, R. Cesário, F. Brandão, V. Pereira, A. Marques, M. Barata, P. Pousão-Ferreira, H. Abreu, M. Pacheco, P. Pereira

28

Marine macroalgae dietary supplementation shields the white seabream (Diplodus sargus) from the chromosomal damage caused by inorganic mercury

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Emerging pollutants I

A. García-Rodríguez, J. Gutiérrez, A. Villacorta, J. Arribas Arranz, I. Romero-Andrada, A. Lacoma, R. Marcos, A. Hernández, L. Rubio

30

Polylactic acid nanoplastics (PLA-NPLs) induce adverse effects on an in vitro model of the human lung epithelium: the Calu-3 air-liquid interface (ALI) barrier

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A. Touzani, L. Ramos-Pan, N. Fernández-Bertólez, L. Martínez, M. L. Díaz-Prado, B. Laffon, V. Valdiglesias

31

Biocompatibility of platinum nanoparticles: study in neuronal cells and Drosophila melanogaster

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J. Arribas Arranz, A. Villacorta, L. Rubio, A. García-Rodríguez, M. Sánchez, M. Llorca, M. Farre, J. F. Ferrer, R. Marcos, A. Hernández

32

Kinetics and toxicity of nanoplastics in ex vivo exposed human whole blood as a model to understand their impact on human health

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L. Ramos-Pan, A. Touzani, N. Fernández-Bertólez, J. Méndez, M. Paz, J. Mosquera, B. Laffon, V. Valdiglesias

33

Analysis of cell cycle, apoptosis rate and DNA damage in neuronal cells exposed to differently charged gold nanoparticles

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M. Alaraby, D. Abass, A. Hernández, R. Marcos

34

Are bioplastics safe? Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila

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A. Rocabert, H. Van Goethem, J. Cabrera, J. Martín, M. Alaraby, A. García-Rodríguez, J. Martínez-Urtaza, R. Marcos, A. Hernández

35

Changes in Drosophila microbiome caused by nanoplastics

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L. Ruano, J. Guitérrez, L. Rubio, R. Egea, A. García, R. Marcos, A. Hernández

36

Long-term exposure of BEAS-2B bronchial cell line to PET nanoplastics

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Gene expression and epigenetics

C. Ayala-Roldán, R. Santiago-Domínguez, L. G. Bermúdez Liscano, C. Bernal Forigua, J. Romero Simmonds, M. I. Martínez Macías, B. Jurado Gómez, L. Caballero Ballesteros, M. S. Arenas de Larriva, R. R. Ariza, T. Roldán-Arjona, A. P. Rojas Moreno, T. Morales-Ruiz

38

RASSF1A methylation analysis in minimally invasive samples from lung cancer patients and individuals with risk factors

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Emerging pollutants II

A. Rodríguez-Garraus, M. Venäläinen, J. Lyyränen, H. Pulli, A. Salmatonidis, D. Lotti, J. Domenech, J. F. Fernández, J. Guzmán-Mínguez, A. Katsumiti, I. Rodríguez-Llopis, S. Vázquez-Campos, M. Carriere, J. Catalán

40

Plastic particles derived from 3D printed objects, assessment of their cellular transforming potential

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J. Gutiérrez, J. Domenech, I. Barguilla, M. Morataya, L. Rubio, B. Guyot, R. Marcos, V. Maguer-Satta, J. Catalán, A. Hernández

41

Carcinogenicity of micro- & nanoplastics long-term exposure

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M. Morataya-Reyes, A. Villacorta, J. Arribas, J. Gutiérrez, L. Rubio, R. Marcos, A. Hernández

42

Exploring the Carcinogenic Potential of PET Nanoplastics Co-exposure with Cigarette Smoke Condensate: A Long-Term In Vitro Study Using BEAS-2B Cells

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J. Martín-Pérez, A. Villacorta, G. Banaei, M. Morataya-Reyes, A. Tavakolpournegari, R. Marcos, A. Hernández, A. García-Rodríguez

43

Hazard assessment of nanoplastics is driven by their surface-functionalization. Effects in human-derived primary endothelial cells

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A. Villacorta, C. Cazorla-Ares, V. Fuentes-Cebrián, I. H. Valido, L. Vela, F. Carrillo-Navarrete, M. Morataya-Reyes, K. Mejía-Carmona, S. Pastor, A. Velázquez, J. Arribas Arranz, R. Marcos, M. López-Mesas, A. Hernández

44

Fluorescent labeling of micro/nanoplastics for biological applications with a focus on “true-to-life" tracking

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V. V. Tkach, N. M. Storoshchuk, I. Gaivão, Y. G. Ivanushko, P. I. Yagodynets, T. V. Morozova, J. I. Martins, J. R. Garcia

45

Electrochemical sensor for sucralose and its genotoxic ester. A mathematical description

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